Parkinson’s Disease

Revolutionizing the way Parkinson’s is treated by focusing on the cause

Want to find out if Mannitol can help Parkinson’s ?

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ABOUT OUR PROGRAM

CliniCrowd is a global community for Parkinson’s patients and those at-risk to share their experiences, treatments, and insights. The goal of the site is to provide you with science-based, safe solutions to help you manage your disease.

By joining CliniCrowd, you can easily track your disease progress and make educated decisions about which treatments work best for you. The wisdom of the crowd will be used to test whether treatments are effective enough to achieve desired outcomes while allowing you to compare your status with your community members.

HOW TO JOIN THE PARKINSON’S REGISTRY?

Sign in to CliniCrowd website
click here  to Sign in
Fill out the Parkinson’s Initial Registry
Main menu >> Registries or click here (once you are logged in)
Get relevant information about Mannitol
Once you submit the registry, you will be directed to a page with detailed information such as; where to purchase, recommended dosage according to research, usage, side affects
and more
Fill out the Parkinson’s Follow Up Registry on a monthly basis
go to Main menu >> Registries or click here

MANNITOL

CliniCrowd Parkinson’s registry is driven by pre-clinical studies conducted by Professor Daniel Segal and Professor Ehud Gazit at Tel Aviv University in Israel and by Professor Eliezer Masliah at the University of California, San Diego. See publication

Alpha synuclein is an abundant protein in the brain especially in the presynaptic terminal of neurons. It plays a role in maintaining vesicles for the neurotransmitters in the nerve endings. Parkinson’s disease (PD) is characterized by degeneration and loss of neurons particularly those crucial for coordination of movements. According to the Michael J. Fox Foundation it is the pathological hallmark of Parkinson’s. Significant research has been done in the areas of preventing excess alpha synuclein formation or clumping and disruption of the already existing clumps.

Mannitol, a common low calorie sweetener, found by the FDA to be generally recognized as safe (GRAS) food additive (See link to FDA site and link to EFSA site.), has shown the ability to diminish alpha synuclein in the test tube, fruit flies, and mice, and improved their Parkinson’s-like symptoms. To date, several Parkinson’s patients who have read the scientific data have decided they have nothing to lose by trying Mannitol as a sweetener. Some of them have reported improvement in their Parkinson’s grade and symptoms.

MANAGE YOUR OWN DISEASE – JOIN REGISTRY

We’d like to invite you to join the Crowd to see if you, too, can benefit from Mannitol.

Click below to enter the registry: first time and returning participants

JOIN INITIAL REGISTRY
FOLLOW-UP REGISTRY

Testimonials

FORUM

INTRODUCTION TO PARKINSON’S FORUM

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FAQ

PD FREQUENTLY ASKED QUESTIONS

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